業績リスト
臨床研究・人を対象とした研究
One-year trajectories of postpartum depressive symptoms and associated psychosocial factors: findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Kikuchi S, Murakami K, Obara T, Ishikuro M, Ueno F, Noda A, Onuma T, Kobayashi N, Sugawara J, Yamamoto M, Yaegashi N, Kuriyama S, Tomita H. Journal of Affective Disorders. 295, 632-638. 2021 December doi.org/10.1016/j.jad.2021.08.118
Effect of a novel nasal oxytocin spray with enhanced bioavailability on autism: A randomised trial. Yamasue H, Kojima M, Kuwabara H, Kuroda M, Matsumoto K, Kanai C, Inada N, Owada K, Ochi K, Ono N, Benner S, Wakuda T, Kameno Y, Inoue J, Harada T, Tsuchiya K, Umemura K, Yamauchi A, Ogawa N, Kushima I, Ozaki N, Suyama S, Saito T, Uemura Y, Hamada J, Kano Y, Honda N, Kikuchi S, Seto M, Tomita H, Miyoshi N, Matsumoto M, Kawaguchi Y, Kanai K, Ikeda M, Nakamura I, Isomura S, Hirano Y, Onitsuka T, Kosaka H, Okada T. Brain.
Neural network modeling of altered facial expression recognition in autism spectrum disorders based on predictive processing framework. Takahashi Y, Murata S, Idei H, Tomita H, Yamashita Y. Sci Rep. 11, Article number: 14684, 2021
The return of individual genomic results to research participants: Design and pilot study of Tohoku Medical Megabank Project. Kawame H, Fukushima A, Fuse N, Nagami F, Suzuki Y, Sakurai-Yageta M, Yasuda J, Yamaguchi-Kabata Y, Kinoshita K, Ogishima S, Takai-Igarashi T, Kuriyama S, Hozawa A, Nakaya N, Nakamura T, Minegishi N, Sugawara J, Suzuki K, Tomita H, Uruno A, Kobayashi T, Aizawa Y, Tokutomi T, Yamamoto K, Ohneda K, Kure S, Aoki Y, Katagiri H, Ishigaki Y, Sawada S, Sasaki M, Yamamoto M. J Hum Genet. in press.
White matter volume not associated with hallucinations in clinical high risk and first-episode psychosis: A voxel-based morphometry study. Sato Y, Sakuma A, Ohmuro N, Katsura M, Abe K, Tomimoto K, Iizuka K, Ito F, Tomita H, Matsumoto K. Psychiatry Clin Neurosci. Online ahead of print. 2021 Jun 30 doi: 10.1111/pcn.13284.
Association between OLIG2 Gene SNP rs1059004 and Negative Self-Schema Constructing Trait Factors Underlying Susceptibility to Depression. Komatsu H, Takeuchi H, Ono C, Yu Z, Kikuchi Y, Kakuto Y, Funakoshi S, Ono T, Kawashima R, Taki Y, Tomita H. Front Psychiatry. 12: 631475. 2021 Mar 8 doi: 10.3389/fpsyt.2021.631475.
The delivery of a placenta/fetus with high gonadal steroid production contributes to postpartum depressive symptoms. Kikuchi S, Kobayashi N, Watanabe Z, Ono C, Takeda T, Nishigori H, Yaegashi N, Arima T, Nakai K, Tomita H. Depress Anxiety. 38(4): 422-430. 2021 Apr doi: 10.1002/da.23134.
Sex-Dependent Effects of the APOE ε4 Allele on Behavioral Traits and White Matter Structures in Young Adults. Takeuchi H, Tomita H, Browne R, Taki Y, Kikuchi Y, Ono C, Yu Z, Nouchi R, Yokoyama R, Kotozaki Y, Nakagawa S, Sekiguchi A, Iizuka K, Hanawa S, Araki T, Miyauchi CM, Sakaki K, Nozawa T, Ikeda S, Yokota S, Magistro D, Sassa Y, Kawashima R. Cereb Cortex. 31(1): 672–680. 2021 Jan doi: 10.1093/cercor/bhaa251
Association Between Autistic Symptoms and Self-Stigma in Patients with Schizophrenia Spectrum Disorders. Komatsu H, Ono T, Maita Y, Ishida Y, Kikuchi T, Maki T, Hase S, Sakurai H, Oba A, Teshirogi O, Suzuki A, Mori Y, Shoji C, Fujita A, Takahashi S, Ebina T, Ozaki S, Honma R, Tomita H, Kakuto Y. Neuropsychiatr Dis Treat. 16: 2553-2561. 2020 Oct 29 doi: 10.2147/NDT.S280485.
Prescription patterns in patients with schizophrenia in Japan: First-quality indicator data from the survey of “Effectiveness of Guidelines for Dissemination and Education in psychiatric treatment (EGUIDE)” project. Ichihashi K, Hori H, Hasegawa N, Yasuda Y, Yamamoto T, Tsuboi T, Iwamoto K, Kishimoto T, Horai T, Yamada H, Sugiyama N, Nakamura T, Tsujino N, Nemoto K, Oishi S, Usami M, Katsumoto E, Yamamori H, Tomita H, Suwa T, Furihata R, Inagaki T, Fujita J, Onitsuka T, Miura K, Matsumoto J, Ohi K, Matsui Y, Takaesu Y, Hashimoto N, Iga J, Ogasawara K, Yamada H, Watanabe K, Inada K, Hashimoto R. Neuropsychopharmacol Rep. 40(3): 281-286. 2020 Sep DOI: 10.1002/npr2.12122
Machine learning for effectively avoiding overfitting is a crucial strategy for the genetic prediction of polygenic psychiatric phenotypes. Takahashi Y, Ueki M, Tamiya G, Ogishima S, Kinoshita K, Hozawa A, Minegishi N, Nagami F, Fukumoto K, Otsuka K, Tanno K, Sakata K, Shimizu A, Sasaki M, Sobue K, Kure S, Yamamoto M, Tomita, H. Translational Psychiatry. 10(1) 294 2020, Dec 1: DOI: 10.1038/s41398-020-00957-5
Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity. Komatsu H, Takeuchi H, Kikuchi Y, Ono C, Yu Z, Iizuka K, Takano Y, Kakuto Y, Funakoshi S, Ono T, Ito J, Kunii Y, Hino M, Nagaoka A, Iwasaki Y, Yamamori H, Yasuda Y, Fujimoto M, Azechi H, Kudo N, Hashimoto R, Yabe H, Yoshida M, Saito Y, Kakita A, Fuse N, Kawashima R, Taki Y, Tomita H. Schizophr Bull. 2020 Apr 14:sbaa049. doi: 10.1093/schbul/sbaa049. Online ahead of print.
Improved metabolomic data-based prediction of depressive symptoms using nonlinear machine learning with feature selection. Takahashi Y, Ueki M, Yamada M, Tamiya G, Motoike IN, Saigusa D, Sakurai M, Nagami F, Ogishima S, Koshiba S, Kinoshita K, Yamamoto M, Tomita H. Transl Psychiatry. 2020; 10: 157. Published online. doi: 10.1038/s41398-020-0831-9
A minimal amount of tissue-based pH measurement to improve quality control in neuropsychiatric postmortem brain studies. Ono CT, Yu Z, Kikuchi Y, Kunii Y, Hino M, Matsumoto J, Nagaoka A, Ito J, Iwasaki Y, Hagihara H, Miyakawa T, Yoshida M, Saito Y, Niwa SI, Yabe H, Kakita A, Tomita H. Psychiatry Clin Neurosci. 2019 Sep;73(9):566-573. doi: 10.1111/pcn.12863. Epub 2019 Jun 17.
Genome-wide association meta-analysis and Mendelian randomization analysis confirm ALDH2 influencing on sleep duration in the Japanese population. Nishiyama T, Nakatochi M, Goto A, Iwasaki M, Hachiya T, Sutoh Y, Shimizu A, Wang C, Tanaka H, Watanabe M, Hosono A, Tamai Y, Yamada T, Yamaji T, Sawada N, Fukumoto K, Otsuka K, Tanno K, Tomita H, Kojima K, Nagasaki M, Hozawa A, Hishida A, Sasakabe T, Nishida Y, Hara M, Ito H, Oze I, Nakamura Y, Mikami H, Ibusuki R, Takezaki T, Koyama T, Kuriyama N, Endoh K, Kuriki K, Turin TC, Naoyuki T, Katsuura-Kamano S, Uemura H, Okada R, Kawai S, Naito M, Momozawa Y, Kubo M, Sasaki M, Yamamoto M, Tsugane S, Wakai K, Suzuki S. Sleep. [Epub ahead of print] 2019 Feb 22. doi: 10.1093/sleep/zsz046.
Genome analyses for the Tohoku Medical Megabank Project towards establishment of personalized healthcare. Yasuda J, Kinoshita K, Katsuoka F, Danjoh I, Sakurai-Yageta M, Motoike IN, Kuroki Y, Saito S, Kojima K, Shirota M, Saigusa D, Otsuki A, Kawashima J, Yamaguchi-Kabata Y, Tadaka S, Aoki Y, Mimori T, Kumada K, Inoue J, Makino S, Kuriki M, Fuse N, Koshiba S, Tanabe O, Nagasaki M, Tamiya G, Shimizu R, Takai-Igarashi T, Ogishima S, Hozawa A, Kuriyama S, Sugawara J, Tsuboi A, Kiyomoto H, Ishii T, Tomita H, Minegishi N, Suzuki Y, Suzuki K, Kawame H, Tanaka H, Taki Y, Yaegashi N, Kure S, Nagami F; Tohoku Medical Megabank Project Study Group, Kosaki K, Sutoh Y, Hachiya T, Shimizu A, Sasaki M, Yamamoto M. J Biochem. 165(2): 139-158. 2019 Feb. doi: 10.1093/jb/mvy096.
Federated multi-site longitudinal study of at-risk mental state for psychosis in Japan. Matsumoto K, Katsura M, Tsujino N, Nishiyama S, Nemoto T, Katagiri N, Takahashi T, Higuchi Y, Ohmuro N, Matsuoka H, Suzuki M, Mizuno M. Schizophr Res. 2019 Feb;204:343-352. doi: 10.1016/j.schres.2018.09.001. Epub 2018 Sep 13. PMID: 30219604
The relationship between cognitive insight and cognitive performance among individuals with at-risk mental state for developing psychosis. Ohmuro N, Katsura M, Obara C, Kikuchi T, Hamaie Y, Sakuma A, Iizuka K, Ito F, Matsuoka H, Matsumoto K. Schizophr Res. 2018 Feb;192:281-286. doi: 10.1016/j.schres.2017.04.031. Epub 2017 Apr 22. PMID: 28442249
The associations between quality of life and clinical symptoms in individuals with an at-risk mental state and first-episode psychosis. Ohmuro N, Matsumoto K, Ishii Y, Katsura M, Obara C, Kikuchi T, Hamaie Y, Ito F, Matsuoka H. Psychiatry Res. 2017 Aug;254:54-59. doi: 10.1016/j.psychres.2017.04.031. Epub 2017 Apr 19. PMID: 28448805
Differential impacts of duration of untreated psychosis (DUP) on cognitive function in first-episode schizophrenia according to mode of onset. Ito S, Nemoto T, Tsujino N, Ohmuro N, Matsumoto K, Matsuoka H, Tanaka K, Nishiyama S, Suzuki M, Kinoshita H, Ozawa H, Fujita H, Shimodera S, Kishimoto T, Matsumoto K, Hasegawa T, Mizuno M. Eur Psychiatry. 2015 Nov;30(8):995-1001. doi: 10.1016/j.eurpsy.2015.08.004. Epub 2015 Oct 24. PMID: 26497470
The association between cognitive deficits and depressive symptoms in at-risk mental state: a comparison with first-episode psychosis. Ohmuro N, Matsumoto K, Katsura M, Obara C, Kikuchi T, Hamaie Y, Sakuma A, Iizuka K, Ito F, Matsuoka H. Schizophr Res. 2015 Mar;162(1-3):67-73. doi: 10.1016/j.schres.2015.01.008. Epub 2015 Jan 22. PMID: 25618299
A naturalistic longitudinal study of at-risk mental state with a 2.4 year follow-up at a specialized clinic setting in Japan. Katsura M, Ohmuro N, Obara C, Kikuchi T, Ito F, Miyakoshi T, Matsuoka H, Matsumoto K. Schizophr Res. 2014 Sep;158(1-3):32-8. doi: 10.1016/j.schres.2014.06.013. Epub 2014 Jul 15. PMID: 25034763
Fluorescently activated cell sorting followed by microarray profiling of helper T cell subtypes from human peripheral blood. Ono C, Yu Z, Kasahara Y, Kikuchi Y, Ishii N, Tomita H. PLoS One. 2014 Nov 7;9(11):e111405. doi: 10.1371/journal.pone.0111405. eCollection 2014. PMID: 25379667
Emotional processing during speech communication and positive symptoms in schizophrenia. Ito F, Matsumoto K, Miyakoshi T, Ohmuro N, Uchida T, Matsuoka H. Psychiatry Clin Neurosci. 2013 Nov;67(7):526-31. doi: 10.1111/pcn.12103. Epub 2013 Oct 22. PMID: 24147562
G protein-linked signaling pathways in bipolar and major depressive disorders. Tomita H, Ziegler ME, Kim HB, Evans SJ, Choudary PV, Li JZ, Meng F, Dai M, Myers RM, Neal CR, Speed TP, Barchas JD, Schatzberg AF, Watson SJ, Akil H, Jones EG, Bunney WE, Vawter MP. Front Genet. 2013 Dec 23;4:297. doi: 10.3389/fgene.2013.00297. eCollection 2013. PMID: 24391664
Physical and psychological outcome in long-term survivors of childhood malignant solid tumor in Japan. Honda N, Funakoshi S, Ambo H, Nio M, Hayashi Y, Matsuoka H. Pediatr Surg Int. 2011 Jul;27(7):713-20. doi: 10.1007/s00383-011-2856-x. Epub 2011 Feb 4. PMID: 21293867
Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders. Vawter MP, Tomita H, Meng F, Bolstad B, Li J, Evans S, Choudary P, Atz M, Shao L, Neal C, Walsh DM, Burmeister M, Speed T, Myers R, Jones EG, Watson SJ, Akil H, Bunney WE. Mol Psychiatry. 2006 Jul;11(7):615, 663-79. Epub 2006 Apr 25. PMID: 16636682
Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression. Choudary PV, Molnar M, Evans SJ, Tomita H, Li JZ, Vawter MP, Myers RM, Bunney WE Jr, Akil H, Watson SJ, Jones EG. Proc Natl Acad Sci U S A. 2005 Oct 25;102(43):15653-8. Epub 2005 Oct 17. PMID: 16230605 Free PMC Article
Dysregulation of the fibroblast growth factor system in major depression. Evans SJ, Choudary PV, Neal CR, Li JZ, Vawter MP, Tomita H, Lopez JF, Thompson RC, Meng F, Stead JD, Walsh DM, Myers RM, Bunney WE, Watson SJ, Jones EG, Akil H. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15506-11. Epub 2004 Oct 13. PMID: 15483108
Effect of agonal and postmortem factors on gene expression profile: quality control in microarray analyses of postmortem human brain. Tomita H, Vawter MP, Walsh DM, Evans SJ, Choudary PV, Li J, Overman KM, Atz ME, Myers RM, Jones EG, Watson SJ, Akil H, Bunney WE Jr. Biol Psychiatry. 2004 Feb 15;55(4):346-52. PMID: 14960286
脳画像研究
A single nucleotide polymorphism (-250 A/C) of the GFAP gene is associated with brain structures and cerebral blood flow. Takahashi Y, Takeuchi H, Sakai M, Yu Z, Kikuchi Y, Ito F, Matsuoka H, Tanabe O, Yasuda J, Taki Y, Kawashima R, Tomita H. Psychiatry Clin Neurosci. 2019 Sep 10. doi: 10.1111/pcn.12932. [Epub ahead of print]
rs1360780 of the FKBP5 gene modulates the association between maternal acceptance and regional gray matter volume in the thalamus in children and adolescents. Matsudaira I, Oba K, Takeuchi H, Sekiguchi A, Tomita H, Taki Y, Kawashima R. PLoS One. 2019 Aug 29;14(8):e0221768. doi: 10.1371/journal.pone.0221768. eCollection 2019.
Effect of the interaction between BDNF Val66Met polymorphism and daily physical activity on mean diffusivity. Takeuchi H, Tomita H, Taki Y, Kikuchi Y, Ono C, Yu Z, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Kunitoki K, Sassa Y, Kawashima R. Brain Imaging Behav. 2019 Jan 7. doi: 10.1007/s11682-018-0025-8. [Epub ahead of print] PMID: 30617785
A Common CACNA1C Gene Risk Variant has Sex-Dependent Effects on Behavioral Traits and Brain Functional Activity. Takeuchi H, Tomita H, Taki Y, Kikuchi Y, Ono C, Yu Z, Nouchi R, Yokoyama R, Kotozaki Y, Nakagawa S, Sekiguchi A, Iizuka K, Hanawa S, Araki T, Miyauchi CM, Sakaki K, Nozawa T, Ikeda S, Yokota S, Magistro D, Sassa Y, Kawashima R. Cereb Cortex. 2018 Aug 15. doi: 10.1093/cercor/bhy189. [Epub ahead of print] PMID: 30124797
No regional gray matter volume reduction observed in young Japanese people at ultra-high risk for psychosis: A voxel-based morphometry study. Sakuma A, Obara C, Katsura M, Ito F, Ohmuro N, Iizuka K, Kikuchi T, Miyakoshi T, Matsuoka H, Matsumoto K. Asian J Psychiatr. 2018 Oct;37:167-171. doi: 10.1016/j.ajp.2018.09.009. Epub 2018 Sep 29. PMID: 30293050
Polymorphisms in the microglial marker molecule CX3CR1 affect the blood volume of the human brain. Sakai M, Takeuchi H, Yu Z, Kikuchi Y, Ono C, Takahashi Y, Ito F, Matsuoka H, Tanabe O, Yasuda J, Taki Y, Kawashima R, Tomita H. Psychiatry Clin Neurosci. 2018 Jun;72(6):409-422. doi: 10.1111/pcn.12649. Epub 2018 Apr 10. PMID: 29485193
Open-label study of cognitive behavioural therapy for individuals with at-risk mental state: Feasibility in the Japanese clinical setting. Matsumoto K, Ohmuro N, Tsujino N, Nishiyama S, Abe K, Hamaie Y, Katsura M, Inoue N, Matsuoka H, Kawasaki Y, Kishimoto T, Suzuki M, Mizuno M. Early Interv Psychiatry. 2019 Feb;13(1):137-141. doi: 10.1111/eip.12541. Epub 2018 Jan 22. PMID: 29357194
The VEGF gene polymorphism impacts brain volume and arterial blood volume. Takeuchi H, Tomita H, Taki Y, Kikuchi Y, Ono C, Yu Z, Sekiguchi A, Nouchi R, Kotozaki Y, Nakagawa S, Miyauchi CM, Iizuka K, Yokoyama R, Shinada T, Yamamoto Y, Hanawa S, Araki T, Kunitoki K, Sassa Y, Kawashima R. Hum Brain Mapp. 2017 Jul;38(7):3516-3526. doi: 10.1002/hbm.23606. Epub 2017 Apr 12. PMID: 28402004
精神的健康の心理社会的側面に関する疫学研究
Five-year Psychosocial Impact of Living in Post-Disaster Prefabricated Temporary Housing. Akaishi T, Suzuki T, Nemoto H, Utsumi Y, Seto M, Usukura H, Kunii Y, Sugawara Y, Nakaya N, Nakamura T, Tsuchiya N, Narita A, Kogure M, Hozawa A, Tsuji I, Ishii T, Tomita H. Disaster Med Public Health Prep. Online ahead of print. 2021 Jun 23 doi: 10.1017/dmp.2021.212.
Machine learning to reveal hidden risk combinations for the trajectory of posttraumatic stress disorder symptoms. Takahashi Y, Yoshizoe K, Ueki M, Tamiya G, Zhiqian Y, Utsumi Y, Sakuma A, Tsuda K, Hozawa A, Tsuji I, Tomita H. Sci Rep. 10, 21726. 2020 Dec 10 DOI: https://doi.org/10.1038/s41598-020-78966-z
Impact of the Great East Japan Earthquake on the Employment Status and Mental Health Conditions of Affected Coastal Communities. Katayanagi M, Seto M, Nakaya N, Nakamura T, Tsuchiya N, Narita A, Kogure M, Sugawara Y, Kodaka A, Utsumi Y, Usukura H, Kunii Y, Hozawa A, Tsuji I, Tomita H. Int J Environ Res Public Health. 17(21): 8130. 2020 Nov 3 doi: 10.3390/ijerph17218130.
Onset and remission of common mental disorders among adults living in temporary housing for three years after the triple disaster in Northeast Japan: comparisons with the general population. Kawakami N, Fukasawa M, Sakata K, Suzuki R, Tomita H, Nemoto H, Yasumura S, Yabe H, Horikoshi N, Umeda M, Suzuki Y, Shimoda H, Tachimori H, Takeshima T, Bromet E. BMC Public Health. 20(1): 1271. 2020 Aug 20 DOI: 10.1186/s12889-020-09378-x
Association between the social isolation and depressive symptoms after the great East Japan earthquake: findings from the baseline survey of the TMM CommCohort study. Kotozaki Y, Tanno k, Sakata K, Takusari E, Otsuka K, Tomita H, Sasaki R, Takanashi N, Mikami T, Hozawa A, Nakaya N, Tsuchiya N, Nakamura T, Narita A, Taki Y, Shimizu A, Hitomi J, Satoh M, Sasaki M. BMC Public Health. 21: 925. 2021 May 15 DOI: https://doi.org/10.1186/s12889-021-10896-5
The Impact of Health Consciousness on the Association Between Walking Durations and Mental Health Conditions After a Disaster: a Cross-Sectional Study. Utsumi Y, Nemoto H, Nakaya N, Nakamura T, Tsuchiya N, Narita N, Kogure M, Suzuki T, Seto M, Katayanagi M, Okuyama J, Sakuma A, Honda N, Sugawara Y, Kaye-Kauderer H, Takahashi Y, Kayama A, Kakuto Y, Kohzuki M, Hozawa A, Tsuji I, Tomita H. Sports Med Open. 2020. 6(1):30. doi: 10.1186/s40798-020-00259-6.
Trajectories for Post-traumatic Stress Disorder Symptoms Among Local Disaster Recovery Workers Following the Great East Japan Earthquake: Group-based Trajectory Modeling. Sakuma A, Ueda I, Shoji W, Tomita H, Matsuoka H, Matsumoto K. J Affect Disord. 2020 Sep 1; 274: 742–751. Published online 2020 May 31. doi: 10.1016/j.jad.2020.05.152
Antidepressant prescriptions for prenatal and postpartum women in Japan: A health administrative database study. Ishikawa T, Obara T, Kikuchi S, Kobayashi N, Miyakoda K, Nishigori H, Tomita H, Akazawa M, Yaegashi N, Kuriyama S, Mano N. J Affect Disord. 2020 Mar 1;264:295-303. doi: 10.1016/j.jad.2020.01.016. Epub 2020 Jan 7.
Onset and remission of common mental disorders among adults living in temporary housing for three years after the triple disaster in Northeast Japan: comparisons with the general population. Kawakami N, Fukasawa M, Sakata K, Suzuki R, Tomita H, Nemoto H, Yasumura S, Yabe H, Horikoshi N, Umeda M, Suzuki Y, Shimoda H, Tachimori H, Takeshima T, Bromet E. BMC public health 20(1) 1271, 2020 Aug, DOI: 10.1186/s12889-020-09378-x
Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): Rationale, progress and perspective. Kuriyama S, Metoki H, Kikuya M, Obara T, Ishikuro M, Yamanaka C, Nagai M, Matsubara H, Kobayashi T, Sugawara J, Tamiya G, Hozawa A, Nakaya N, Tsuchiya N, Nakamura T, Narita A, Kogure M, Hirata T, Tsuji I, Nagami F, Fuse N, Arai T, Kawaguchi Y, Higuchi S, Sakaida M, Suzuki Y, Osumi N, Nakayama K, Ito K, Egawa S, Chida K, Kodama E, Kiyomoto H, Ishii T, Tsuboi A, Tomita H, Taki Y, Kawame H, Suzuki K, Ishii N, Ogishima S, Mizuno S, Takai-Igarashi T, Minegishi N, Yasuda J, Igarashi K, Shimizu R, Nagasaki M, Tanabe O, Koshiba S, Hashizume H, Motohashi H, Tominaga T, Ito S, Tanno K, Sakata K, Shimizu A, Hitomi J, Sasaki M, Kinoshita K, Tanaka H, Kobayashi T, Kure S, Yaegashi N, Yamamoto M. International Journal of Epidemiology. 49(1) 18-19M, 2020 Feb, DOI: 10.1093/ije/dyz169
Prescription patterns in patients with schizophrenia in Japan: First-quality indicator data from the survey of “Effectiveness of Guidelines for Dissemination and Education in psychiatric treatment (EGUIDE)” project. Ichihashi K, Hori H, Hasegawa N, Yasuda Y, Yamamoto T, Tsuboi T, Iwamoto K, Kishimoto T, Horai T, Yamada H, Sugiyama N, Nakamura T, Tsujino N, Nemoto K, Oishi S, Usami M, Katsumoto E, Yamamori H, Tomita H, Suwa T, Furihata R, Inagaki T, Fujita J, Onitsuka T, Miura K, Matsumoto J, Ohi K, Matsui Y, Takaesu Y, Hashimoto N, Iga J, Ogasawara K, Yamada H, Watanabe K, Inada K, Hashimoto R. Neuropsychopharmacology Reports. 2020. DOI: 10.1002/npr2.12122
Design and progress of oral health examinations in the tohoku medical megabank project. Tsuboi A, Matsui H, Shiraishi N, Murakami T, Otsuki A, Kawashima J, Kiyama T, Tamahara T, Goto M, Koyama S, Sugawara J, Kodama E, Metoki H, Hozawa A, Kuriyama S, Tomita H, Kikuya M, Minegishi N, Suzuki K, Koshiba S, Tamiya G, Fuse N, Aoki Y, Takai-Igarashi T, Ogishima S, Nakamura T, Sakurai-Yageta M, Nagami F, Kinoshita K, Kure S, Shimizu R, Sasaki K, Yamamoto M. Tohoku Journal of Experimental Medicine. 251(2) 2020, 97-115, DOI: 10.1620/tjem.251.97
Prefabricated Temporary Housing and Eczema or Respiratory Symptoms in Schoolchildren after the Great East Japan Earthquake: The ToMMo Child Health Study. Kuniyoshi Y, Kikuya M, Miyashita M, Yamanaka C, Ishikuro M, Obara T, Metoki H, Nakaya N, Nagami F, Tomita H, Hozawa A, Tsuji I, Kure S, Yaegashi N, Kuriyama S. Disaster Med Public Health Prep. [Epub ahead of print] 2019 Jun 3: doi: 10.1017/dmp.2019.8.
Longitudinal characteristics of resilience among adolescents: A high school student cohort study to assess the psychological impact of the Great East Japan Earthquake. Okuyama J, Funakoshi S, Tomita H, Yamaguchi T, Matsuoka H. Psychiatry Clin Neurosci. 2018 Nov;72(11):821-835. doi: 10.1111/pcn.12772. Epub 2018 Sep 4. PMID: 30058206
Impact of social capital on psychological distress and interaction with house destruction and displacement after the Great East Japan Earthquake of 2011. Tsuchiya N, Nakaya N, Nakamura T, Narita A, Kogure M, Aida J, Tsuji I, Hozawa A, Tomita H. Psychiatry Clin Neurosci. 2017 Jan;71(1):52-60. doi: 10.1111/pcn.12467. Epub 2016 Dec 21. PMID: 27743428
Criticism by community people and poor workplace communication as risk factors for the mental health of local welfare workers after the Great East Japan Earthquake: A cross-sectional study. Ueda I, Sakuma A, Takahashi Y, Shoji W, Nagao A, Abe M, Suzuki Y, Matsuoka H, Matsumoto K. PLoS One. 2017 Nov 22;12(11):e0185930. doi: 10.1371/journal.pone.0185930. eCollection 2017. PMID: 29166390
Post-traumatic growth of children affected by the Great East Japan Earthquake and their attitudes to memorial services and media coverage. Yoshida H, Kobayashi N, Honda N, Matsuoka H, Yamaguchi T, Homma H, Tomita H. Psychiatry Clin Neurosci. 2016 May;70(5):193-201. doi: 10.1111/pcn.12379. Epub 2016 Apr 5. PMID: 26821650
Partners' Ongoing Treatment for Chronic Disease and the Risk of Psychological Distress after the Great East Japan Earthquake. Nakaya N, Narita A, Tsuchiya N, Nakamura T, Tsuji I, Hozawa A, Tomita H. Tohoku J Exp Med. 2016 Aug;239(4):307-14. doi: 10.1620/tjem.239.307. PMID: 27506650
The Tohoku Medical Megabank Project: Design and Mission. Kuriyama S, Yaegashi N, Nagami F, Arai T, Kawaguchi Y, Osumi N, Sakaida M, Suzuki Y, Nakayama K, Hashizume H, Tamiya G, Kawame H, Suzuki K, Hozawa A, Nakaya N, Kikuya M, Metoki H, Tsuji I, Fuse N, Kiyomoto H, Sugawara J, Tsuboi A, Egawa S, Ito K, Chida K, Ishii T, Tomita H, Taki Y, Minegishi N, Ishii N, Yasuda J, Igarashi K, Shimizu R, Nagasaki M, Koshiba S, Kinoshita K, Ogishima S, Takai-Igarashi T, Tominaga T, Tanabe O, Ohuchi N, Shimosegawa T, Kure S, Tanaka H, Ito S, Hitomi J, Tanno K, Nakamura M, Ogasawara K, Kobayashi S, Sakata K, Satoh M, Shimizu A, Sasaki M, Endo R, Sobue K, Tohoku Medical Megabank Project Study Group T, Yamamoto M. J Epidemiol. 2016 Sep 5;26(9):493-511. doi: 10.2188/jea.JE20150268. Epub 2016 Jul 2. PMID: 27374138
Prospect of future housing and risk of psychological distress at 1 year after an earthquake disaster. Nakaya N, Nakamura T, Tsuchiya N, Narita A, Tsuji I, Hozawa A, Tomita H. Psychiatry Clin Neurosci. 2016 Apr;70(4):182-9. doi: 10.1111/pcn.12377. Epub 2016 Jan 14. PMID: 26661684
Unemployment risk among individuals undergoing medical treatment for chronic diseases. Nakaya N, Nakamura T, Tsuchiya N, Tsuji I, Hozawa A, Tomita H. Occup Med (Lond). 2016 Mar;66(2):143-9. doi: 10.1093/occmed/kqv159. Epub 2015 Nov 13. PMID: 26567288
The Association Between Medical Treatment of Physical Diseases and Psychological Distress After the Great East Japan Earthquake: The Shichigahama Health Promotion Project. Nakaya N, Nakamura T, Tsuchiya N, Tsuji I, Hozawa A, Tomita H. Disaster Med Public Health Prep. 2015 Aug;9(4):374-81. doi: 10.1017/dmp.2015.52. Epub 2015 Apr 27. PMID: 25912962
災害メンタルヘルスに関する質的研究
Experiences of perinatal women and public healthcare providers in a community affected by the great east Japan earthquake and tsunami: Concerns that must be considered for the mental healthcare of perinatal women in postdisaster settings. Kobayashi N, Nemoto H, Seto M, Sato S, Kikuchi S, Honda N, Suzuki T, Sato K, Sugawara J, Ito K, Kayano R, Ozaki N, Beadling CW, Kelman I, Imamura F, Matsuoka H, Tomita H. International Journal of Disaster Risk Reduction 2020 51 101767. https://doi.org/10.1016/j.ijdrr.2020.101767
Post-disaster mental health and psychosocial support in the areas affected by the Great East Japan Earthquake: a qualitative study. Seto M, Nemoto H, Kobayashi N, Kikuchi S, Honda N, Kim Y, Kelman I, Tomita H. BMC Psychiatry. 2019 Aug 27;19(1):261. doi: 10.1186/s12888-019-2243-z.
モデル動物・培養細胞を用いた研究
Tumor necrosis factor α negatively regulates the retrieval and reconsolidation of hippocampus-dependent memory. Takahashi S, Fukushima H, Yu Z, Tomita H, Kida S. Brain Behav Immun. 94: 79-88. 2021 May doi: 10.1016/j.bbi.2021.02.033
Microglial production of TNF-alpha is a key element of sustained fear memory. Yu Z, Fukushima H, Ono C, Sakai M, Kasahara Y, Kikuchi Y, Gunawansa N, Takahashi Y, Matsuoka H, Kida S, Tomita H. Brain Behav Immun. 2017 Jan;59:313-321. doi: 10.1016/j.bbi.2016.08.011. Epub 2016 Aug 22.
PMID: 27562421Therapeutic concentration of lithium stimulates complement C3 production in dendritic cells and microglia via GSK-3 inhibition. Yu Z, Ono C, Aiba S, Kikuchi Y, Sora I, Matsuoka H, Tomita H. Glia. 2015 Feb;63(2):257-70. doi: 10.1002/glia.22749. Epub 2014 Sep 1. PMID: 25179772
Four mood stabilizers commonly induce FEZ1 expression in human astrocytes. Yu Z, Ono C, Kim HB, Komatsu H, Tanabe Y, Sakae N, Nakayama KI, Matsuoka H, Sora I, Bunney WE, Tomita H. Bipolar Disord. 2011 Aug-Sep;13(5-6):486-99. doi: 10.1111/j.1399-5618.2011.00946.x. PMID: 22017218
Novel truncated isoform of SK3 potassium channel is a potent dominant-negative regulator of SK currents: implications in schizophrenia. Tomita H, Shakkottai VG, Gutman GA, Sun G, Bunney WE, Cahalan MD, Chandy KG, Gargus JJ. Mol Psychiatry. 2003 May;8(5):524-35, 460. Erratum in: Mol Psychiatry. 2003 Aug;8(8):766. PMID: 12808432
